Methionine-enkephalin inhibits stress-induced increases in noradrenaline turnover in brain regions of rats.
نویسندگان
چکیده
Met-Enkephalin injected i.c.v. attenuated stress-induced increases in levels of 3-methoxy-4-hydroxyphenylethyleneglycol sulfate, the major metabolite of brain noradrenaline, in the hypothalamus, amygdala, hippocampus, thalamus, midbrain and LC region in rats. The data suggest that Met-enkephalin acts to attenuate stress-induced increases in noradrenaline turnover in these brain regions in rats.
منابع مشابه
Bilateral adrenalectomy does not alter stress-induced increases in noradrenaline turnover in rat brain regions.
Effects of adrenalectomy on increases in noradrenaline (NA) turnover induced by a one-hour immobilization stress were examined by measuring the levels of NA and its major metabolite, 3-methoxy-4-hydroxyphenylethyleneglycol sulfate (MHPG-SO4) in specific brain regions of the rat. Bilateral adrenalectomy alone does not affect basal levels of NA and MHPG-SO4 in the brain regions examined with the ...
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عنوان ژورنال:
- Japanese journal of pharmacology
دوره 37 1 شماره
صفحات -
تاریخ انتشار 1985